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Our reagents for the synthesis of DNA and RNA oligonucleotides are produced and packaged to ensure the highest performance on commercial synthesizers.

Our universal supports and synthesis supplies are produced and packaged to ensure the highest performance on commercial oligonucleotide synthesizers.

Glen Research ancillary reagents are produced and packaged to ensure the highest performance on commercial oligonucleotide synthesizers.

Our products for oligonucleotide modification and labeling are produced and packaged to ensure the highest performance on commercial synthesizers.

Since the DMT group binds strongly to reverse phase supports, the full-length sequences can be retained in a cartridge while the failure sequences are eluted.

 

Glen Report Newsletter

Glen Report Volume 35.2 is now available.

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Featured Article

2'-OMe-N6-Me-A-CE Phosphoramidite

2’-OMe-N6-Me-A, commonly referred to as m6Am, is a crucial component of the 5’-cap of mRNA. 2’-OMe-A is often the first transcribed nucleotide, and this modification is a result of methylation at the N6-position of the nucleobase. The 5’-cap structures initiate translation and protect RNA from degradation. Internal m6Am have also been implicated in regulating gene expression, RNA splicing, and cancer proliferation. Read more!

 

Explore Oligonucleotide Applications

Glen Research offers a wide range of products for oligonucleotide applications.

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Design of Fluorescent Probes

Glen Research offers a wide selection of fluorophores and fluorescence quenchers, which can be added during oligonucleotide synthesis at the 5′- or 3’-terminus or within the sequence. The resultant fluorescent oligonucleotide probes are typically used in a wide variety of applications like genetic and genome analyses, and forensic analysis. Common applications of fluorescent oligonucleotide probes are FRET and Molecular Beacon probes.

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